Metabolic Flexibility: How Your Body Balances Glucose and Fat After 45
How your body decides between burning sugar or fat — and why that choice changes in midlife.
Good Morning, Afternoon or Evening,
Energy isn’t just about what you eat — it’s about how easily your body switches between glucose and fat for fuel.
After 45, that balance can change as estrogen, thyroid, and muscle activity shift, making steady energy feel harder to hold onto.
In this short episode, we explore metabolic flexibility — the ability to move smoothly between fuel sources — and why it becomes one of the most important markers of metabolic health in midlife.
You’ll hear how genes like PPARGC1A, FADS1, FADS2, and ADIPOQ influence insulin sensitivity, energy stability, and the way your cells decide what to burn first. It’s a simple but powerful look at how your design guides your metabolism.
If you’ve noticed more hunger between meals or energy swings that didn’t used to happen, this episode will help you understand what’s really going on underneath — and how to support your body’s natural rhythm again.
🧬 Mentioned in this series: The Oxygen Connection — a free resource that expands on how oxygen and glucose work together to create steady energy after 45. Learn more.


